Clicking and Dragging
Clicking and dragging can be extremely painful for anyone with RSI or carpal tunnel, no matter what input device you use.
Even with my Wacom tablet, clicking and dragging is the most painful computer activity that I can think of.
The other day I had some files to sort. I was clicking them and then dragging them into various folders. After less than an hour, my entire arm, from my fingertips to my shoulder, was in severe pain.
I would have worn a sling if I had one, since the pain was so bad. Instead, I went to bed, like I always do when I encounter severe pain and can't stop it in any other way.
